QUIM8995 Bioinformatics, Proteins, & PPI's

Bioinformatics, Proteins, and Protein-Protein Interactions QUIM8995

Four credits, four hours of lectures per week. Pre-requisite: Advanced Biochemistry (QUIM6715)

Bioinformatics its basic concepts, methods, and tools to assess protein sequence structure and function; and the use of molecular biophysics to study proteins and protein-protein interactions.Specifically, the students will have a hands-on approach to using bioinformatics databases to analyze sequences, phylogeny, protein homology, identifying common protein motifs and domains, and protein-protein interactions.Advanced analysis of thermodynamic and spectroscopic data will be performed to understand protein unfolding, relative stability, and protein-protein interactions.Molecular modeling will also be used to discuss protein structure and protein complexes.